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13.78 24.46 c 14.09 23.88 13.87 23.18 13.18 22.82 c 12.5 22.46 11.8 22.66 11.49 23.25 c f 12.96 25.62 m 12.81 25.91 12.8 25.92 12.7 25.9 c 12.58 25.87 12.32 25.76 11.82 25.55 c 11.3 25.35 11.04 25.24 10.93 25.18 c 10.84 25.13 10.84 25.12 10.94 24.8 c 10.81 24.75 l 10.3 25.98 l 10.23 26.17 10.13 26.36 10.06 26.48 c 10.21 26.54 10.58 26.73 10.66 26.79 c 10.74 26.66 l 10.35 26.39 10.34 26.31 10.52 25.85 c 10.64 25.55 l 10.66 25.51 10.68 25.5 10.73 25.52 c 11.48 25.82 l 11.52 25.84 11.54 25.86 11.5 25.95 c 11.46 26.05 l 11.31 26.4 11.25 26.4 11 26.34 c 10.95 26.49 l 11.05 26.53 11.16 26.56 11.32 26.63 c 11.46 26.68 11.6 26.74 11.69 26.78 c 11.75 26.64 l 11.52 26.52 11.48 26.45 11.58 26.2 c 11.68 25.97 l 11.69 25.93 11.71 25.92 11.76 25.94 c 12.56 26.26 l 12.65 26.29 12.64 26.32 12.52 26.7 c 12.66 26.76 l 13.1 25.67 l 12.96 25.62 l h f 11.83 28.59 m 11.72 28.94 11.7 28.96 11.6 28.95 c 11.49 28.93 11.21 28.87 10.67 28.74 c 10.14 28.62 9.87 28.55 9.75 28.51 c 9.65 28.48 9.65 28.45 9.71 28.1 c 9.56 28.07 l 9.28 29.26 l 9.43 29.3 l 9.53 28.94 9.55 28.93 9.65 28.94 c 9.72 28.95 9.93 28.99 10.1 29.03 c 10.32 29.09 l 10.43 29.11 10.44 29.12 10.42 29.21 c 10.21 30.12 l 10.18 30.21 10.17 30.22 10.07 30.19 c 9.83 30.14 l 9.67 30.1 9.46 30.05 9.39 30.03 c 9.3 29.99 9.29 29.97 9.35 29.61 c 9.21 29.58 l 8.92 30.77 l 9.07 30.81 l 9.18 30.46 9.19 30.44 9.29 30.45 c 9.41 30.47 9.69 30.53 10.22 30.66 c 10.76 30.79 11.03 30.85 11.15 30.89 c 11.24 30.92 11.25 30.95 11.19 31.3 c 11.34 31.34 l 11.62 30.14 l 11.47 30.11 l 11.36 30.45 11.35 30.47 11.25 30.46 c 11.15 30.45 10.87 30.39 10.46 30.29 c 10.36 30.27 10.35 30.26 10.37 30.16 c 10.58 29.26 l 10.6 29.16 10.62 29.16 10.72 29.18 c 11.13 29.27 11.41 29.34 11.5 29.38 c 11.6 29.41 11.6 29.43 11.54 29.79 c 11.69 29.83 l 11.97 28.63 l 11.83 28.59 l h f 11.19 31.42 m 11.12 31.75 11.11 31.76 11.01 31.76 c 10.89 31.76 10.61 31.73 10.06 31.66 c 9.52 31.59 9.23 31.56 9.12 31.53 c 9.02 31.51 9.01 31.49 9.03 31.16 c 8.88 31.14 l 8.71 32.47 l 8.69 32.67 8.65 32.87 8.61 33.01 c 8.78 33.04 9.18 33.12 9.27 33.15 c 9.32 33.01 l 8.87 32.85 8.83 32.78 8.89 32.28 c 8.93 31.96 l 8.93 31.92 8.96 31.91 9.01 31.91 c 9.81 32.01 l 9.87 32.01 9.87 32.02 9.87 32.13 c 9.85 32.23 l 9.8 32.61 9.74 32.63 9.48 32.63 c 9.47 32.78 l 9.59 32.8 9.69 32.8 9.87 32.82 c 10.01 32.84 10.17 32.87 10.27 32.88 c 10.28 32.73 l 10.03 32.67 9.98 32.61 10.01 32.34 c 10.04 32.1 l 10.04 32.05 10.06 32.04 10.11 32.04 c 11 32.15 l 11.05 32.16 11.07 32.18 11.07 32.22 c 11 32.82 l 10.96 33.11 10.88 33.17 10.64 33.22 c 10.39 33.26 l 10.41 33.43 l 10.61 33.41 10.95 33.41 11.1 33.42 c 11.34 31.44 l 11.19 31.42 l h f 10.02 35.1 m 10.02 35.13 10.01 35.15 10.01 35.15 c 9.98 35.15 9.95 35.13 9.92 35.12 c 9.04 34.77 l 9.96 34.43 l 9.98 34.42 10 34.41 10.02 34.41 c 10.03 34.41 10.04 34.43 10.04 34.45 c 10.02 35.1 l h 10.92 33.6 m 10.89 33.87 10.81 33.92 10.5 34.03 c 8.95 34.62 l 8.69 34.72 8.62 34.75 8.49 34.78 c 8.49 34.97 l 8.6 34.98 8.79 35.05 8.9 35.1 c 10.61 35.84 l 10.84 35.93 10.88 35.96 10.87 36.26 c 11.02 36.26 l 11.04 35.04 l 10.89 35.04 l 10.87 35.4 10.84 35.43 10.75 35.43 c 10.67 35.43 10.28 35.27 10.24 35.24 c 10.22 35.23 10.21 35.22 10.21 35.2 c 10.2 35.11 10.2 34.93 10.2 34.57 c 10.21 34.35 10.23 34.34 10.31 34.31 c 10.52 34.22 10.71 34.17 10.75 34.17 c 10.85 34.18 10.88 34.21 10.9 34.55 c 11.05 34.55 l 11.07 33.6 l 10.92 33.6 l h f 10.89 36.34 m 10.89 36.68 10.89 36.7 10.79 36.72 c 10.67 36.74 10.39 36.76 9.84 36.81 c 9.3 36.86 9.01 36.88 8.89 36.88 c 8.79 36.88 8.78 36.86 8.72 36.53 c 8.57 36.54 l 8.67 37.68 l 8.82 37.67 l 8.82 37.33 8.82 37.31 8.92 37.29 c 9 37.27 9.2 37.25 9.37 37.23 c 10.78 37.11 l 10.91 37.1 10.94 37.14 10.95 37.24 c 10.98 37.65 l 11.01 37.99 10.91 38.05 10.43 38.29 c 10.5 38.45 l 10.62 38.4 11.03 38.31 11.21 38.29 c 11.04 36.33 l 10.89 36.34 l h f 11.12 38.68 m 11.16 39.06 11.16 39.08 11.06 39.11 c 10.99 39.13 10.87 39.16 10.66 39.2 c 9.05 39.47 l 8.99 39.07 l 8.96 38.95 9.05 38.88 9.44 38.67 c 9.37 38.51 l 9.24 38.57 9.05 38.63 8.73 38.7 c 8.75 38.76 8.77 38.83 8.78 38.9 c 8.81 38.96 8.82 39.03 8.83 39.1 c 9.04 40.31 l 9.06 40.45 9.08 40.59 9.08 40.72 c 9.4 40.68 9.6 40.67 9.74 40.67 c 9.75 40.51 l 9.32 40.43 9.21 40.4 9.19 40.28 c 9.12 39.88 l 10.73 39.6 l 10.94 39.57 11.06 39.55 11.13 39.55 c 11.23 39.54 11.25 39.56 11.34 39.93 c 11.49 39.91 l 11.27 38.66 l 11.12 38.68 l h f 11.4 40.38 m 11.47 40.73 11.47 40.76 11.38 40.79 c 11.26 40.84 10.99 40.92 10.46 41.07 c 9.93 41.22 9.66 41.29 9.54 41.32 c 9.44 41.33 9.43 41.32 9.3 40.97 c 9.16 41.01 l 9.49 42.19 l 9.64 42.16 l 9.56 41.8 9.57 41.78 9.66 41.74 c 9.73 41.71 9.93 41.65 10.09 41.6 c 10.32 41.53 l 10.42 41.51 10.44 41.51 10.46 41.6 c 10.72 42.5 l 10.74 42.59 10.73 42.6 10.63 42.63 c 10.4 42.7 l 10.24 42.75 10.04 42.8 9.96 42.81 c 9.86 42.83 9.84 42.81 9.72 42.47 c 9.58 42.51 l 9.91 43.69 l 10.06 43.65 l 9.99 43.29 9.99 43.27 10.08 43.24 c 10.2 43.19 10.47 43.11 11 42.96 c 11.53 42.81 11.8 42.74 11.92 42.71 c 12.02 42.7 12.03 42.71 12.16 43.06 c 12.3 43.02 l 11.97 41.83 l 11.82 41.87 l 11.9 42.23 11.89 42.25 11.8 42.29 c 11.71 42.33 11.43 42.41 11.03 42.52 c 10.93 42.55 10.91 42.54 10.88 42.46 c 10.63 41.56 l 10.61 41.47 10.61 41.46 10.72 41.42 c 11.12 41.32 11.4 41.24 11.5 41.22 c 11.59 41.2 11.61 41.22 11.73 41.56 c 11.88 41.52 l 11.54 40.34 l 11.4 40.38 l h f 13 45.15 m 13.06 45.26 13.07 45.41 13.04 45.59 c 12.73 45.51 12.12 45.46 11.83 45.46 c 11.84 45.19 11.91 45.03 12.14 44.92 c 12.39 44.81 12.85 44.83 13 45.15 c 11.69 45.8 m 11.7 45.99 11.56 46.14 11.43 46.2 c 11.31 46.26 11.13 46.27 11.05 46.12 c 11.01 46.01 11.03 45.87 11.2 45.8 c 11.3 45.75 11.47 45.73 11.69 45.8 c 13.72 46.55 m 13.76 46.33 13.74 46.12 13.67 45.97 c 13.59 45.81 13.46 45.72 13.19 45.63 c 13.26 45.39 13.27 45.14 13.14 44.88 c 12.93 44.43 12.5 44.34 12.16 44.5 c 11.85 44.65 11.7 44.92 11.69 45.44 c 11.31 45.41 11.18 45.42 11.06 45.47 c 10.85 45.57 10.72 45.8 10.89 46.16 c 11.03 46.47 11.26 46.61 11.53 46.48 c 11.79 46.35 11.84 46.09 11.83 45.83 c 12.21 45.85 12.57 45.88 12.93 45.94 c 12.85 46.14 12.7 46.36 12.59 46.41 c 12.5 46.46 12.43 46.42 12.34 46.29 c 12.21 46.35 l 12.56 47.1 l 12.7 47.03 l 12.62 46.86 12.63 46.71 12.79 46.5 c 12.87 46.4 12.99 46.21 13.1 45.98 c 13.39 46.04 13.47 46.08 13.54 46.21 c 13.59 46.32 13.59 46.45 13.57 46.63 c 13.72 46.55 l h f 14.32 47.61 m 14.51 47.92 14.51 47.95 14.44 48.01 c 14.35 48.1 14.12 48.25 13.66 48.57 c 13.22 48.89 12.98 49.05 12.88 49.11 c 12.79 49.16 12.77 49.15 12.54 48.86 c 12.41 48.95 l 13.12 49.96 l 13.24 49.87 l 13.06 49.56 13.05 49.53 13.13 49.47 c 13.19 49.42 13.35 49.29 13.5 49.19 c 13.69 49.06 l 13.77 49 13.79 49 13.84 49.08 c 14.38 49.84 l 14.43 49.92 14.43 49.94 14.34 50 c 14.14 50.13 l 14.01 50.23 13.83 50.34 13.76 50.39 c 13.68 50.43 13.66 50.42 13.43 50.14 c 13.31 50.22 l 14.01 51.23 l 14.14 51.14 l 13.95 50.83 13.95 50.81 14.02 50.75 c 14.11 50.66 14.34 50.5 14.79 50.18 c 15.24 49.87 15.47 49.71 15.58 49.65 c 15.67 49.6 15.69 49.61 15.92 49.89 c 16.05 49.81 l 15.34 48.8 l 15.21 48.88 l 15.4 49.19 15.4 49.22 15.33 49.28 c 15.25 49.35 15.02 49.52 14.67 49.76 c 14.59 49.82 14.57 49.82 14.52 49.74 c 13.98 48.98 l 13.93 48.9 13.93 48.88 14.02 48.83 c 14.36 48.58 14.6 48.42 14.69 48.37 c 14.78 48.33 14.8 48.34 15.03 48.62 c 15.15 48.53 l 14.44 47.53 l 14.32 47.61 l h f 14.28 51.56 m 15.1 52.47 l 15.22 52.38 l 14.99 52.09 14.99 52.07 15.05 51.99 c 15.13 51.9 15.34 51.71 16.01 51.11 c 16.22 50.92 16.6 50.68 16.97 51.09 c 17.39 51.55 17.21 51.82 16.67 52.31 c 16.24 52.71 16.03 52.89 15.93 52.96 c 15.85 53.02 15.83 53.01 15.55 52.75 c 15.44 52.85 l 16.13 53.6 l 16.24 53.51 l 16.02 53.22 16.01 53.19 16.07 53.12 c 16.16 53.03 16.37 52.84 16.94 52.32 c 17.35 51.95 17.69 51.55 17.08 50.88 c 16.71 50.47 16.22 50.37 15.72 50.81 c 15.07 51.4 14.86 51.59 14.76 51.66 c 14.68 51.72 14.66 51.71 14.39 51.46 c 14.28 51.56 l h f 17.81 52.03 m 18.09 52.3 18.09 52.32 18.04 52.4 c 17.97 52.5 17.78 52.72 17.43 53.13 c 17.06 53.55 16.88 53.76 16.79 53.85 c 16.71 53.91 16.7 53.91 16.39 53.68 c 16.29 53.79 l 17.02 54.42 l 17.03 54.4 17.07 54.37 17.1 54.35 c 18.8 53.37 l 18.8 53.38 l 18.06 55.32 l 18.78 55.93 l 18.88 55.81 l 18.6 55.54 18.59 55.52 18.65 55.44 c 18.71 55.34 18.9 55.13 19.25 54.71 c 19.62 54.29 19.8 54.07 19.89 53.99 c 19.96 53.93 19.98 53.93 20.29 54.17 c 20.39 54.05 l 19.45 53.24 l 19.35 53.36 l 19.62 53.62 19.62 53.65 19.57 53.71 c 18.28 55.21 l 18.28 55.2 l 19.05 53.21 l 19.07 53.15 19.09 53.09 19.12 53.03 c 18.91 52.85 l 18.89 52.88 18.84 52.91 18.79 52.94 c 16.91 54.03 l 16.9 54.02 l 17.98 52.77 l 18.05 52.69 18.17 52.58 18.21 52.54 c 18.28 52.48 18.3 52.48 18.58 52.69 c 18.68 52.58 l 17.91 51.91 l 17.81 52.03 l h f 21.26 55.82 m 21.28 55.83 21.29 55.85 21.28 55.86 c 21.27 55.87 21.24 55.89 21.22 55.91 c 20.45 56.47 l 20.65 55.51 l 20.65 55.49 20.66 55.47 20.67 55.46 c 20.67 55.44 20.7 55.45 20.71 55.46 c 21.26 55.82 l h 20.46 54.26 m 20.67 54.43 20.67 54.53 20.6 54.84 c 20.27 56.47 l 20.22 56.74 20.2 56.81 20.17 56.95 c 20.32 57.04 l 20.4 56.96 20.56 56.83 20.66 56.77 c 22.19 55.71 l 22.39 55.57 22.43 55.55 22.68 55.71 c 22.77 55.58 l 21.75 54.93 l 21.66 55.05 l 21.96 55.26 21.97 55.3 21.91 55.38 c 21.88 55.44 21.53 55.69 21.49 55.71 c 21.47 55.72 21.46 55.72 21.44 55.71 c 21.36 55.66 21.2 55.58 20.9 55.38 c 20.71 55.26 20.72 55.24 20.73 55.15 c 20.78 54.93 20.83 54.74 20.85 54.71 c 20.91 54.62 20.95 54.62 21.25 54.78 c 21.33 54.65 l 20.54 54.14 l 20.46 54.26 l h f 22.79 55.77 m 23.09 55.94 23.1 55.96 23.06 56.05 c 23.02 56.17 22.9 56.42 22.65 56.92 c 22.41 57.41 22.28 57.66 22.21 57.76 c 22.16 57.85 22.14 57.85 21.82 57.72 c 21.76 57.85 l 22.41 58.18 l 22.45 58.15 22.51 58.12 22.57 58.08 c 24.3 57.11 l 24.3 57.12 l 24.05 57.61 l 23.81 58.1 23.68 58.35 23.62 58.46 c 23.57 58.55 23.54 58.55 23.19 58.4 c 23.12 58.53 l 24.02 58.98 l 24.09 58.85 l 23.79 58.7 23.77 58.66 23.85 58.48 c 23.92 58.31 24.01 58.11 24.1 57.94 c 24.41 57.32 24.67 56.8 24.82 56.56 c 24.58 56.45 l 24.33 56.63 24.12 56.76 23.83 56.91 c 22.5 57.65 l 22.5 57.64 l 22.82 57 l 23.06 56.51 23.19 56.25 23.25 56.15 c 23.31 56.06 23.33 56.06 23.73 56.23 c 23.79 56.1 l 22.85 55.63 l 22.79 55.77 l h f 26.51 58.16 m 26.75 57.78 27.01 57.57 27.38 57.68 c 27.75 57.79 27.87 58.07 27.81 58.28 c 27.74 58.51 27.54 58.53 27.28 58.54 c 26.98 58.55 l 26.32 58.56 26.18 58.75 26.1 59.01 c 25.97 59.45 26.24 59.86 26.76 60.02 c 27.02 60.1 27.26 60.13 27.45 60.14 c 27.46 60.1 27.47 60.04 27.49 59.99 c 27.55 59.83 27.6 59.67 27.67 59.5 c 27.51 59.45 l 27.32 59.86 27.08 59.94 26.75 59.84 c 26.46 59.75 26.29 59.49 26.35 59.28 c 26.4 59.13 26.51 59.05 26.79 59.03 c 27.41 59.01 l 27.82 58.99 28.02 58.85 28.11 58.53 c 28.25 58.08 27.97 57.68 27.42 57.51 c 27.17 57.43 26.88 57.46 26.64 57.38 c 26.58 57.56 26.46 57.86 26.36 58.08 c 26.51 58.16 l h f 28.48 58.05 m 28.8 58.15 28.81 58.16 28.8 58.26 c 28.79 58.38 28.73 58.66 28.62 59.19 c 28.51 59.73 28.45 60.01 28.41 60.13 c 28.38 60.22 28.36 60.22 28.04 60.19 c 28.01 60.33 l 29.31 60.6 l 29.51 60.65 29.71 60.71 29.84 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Public Health Service, the Centers for Disease Control and Prevention, or the authors affiliated institutions.)Tj 0 g ET Q 0.50196 0.50196 0.50196 RG 1 w 30 53 m 582 53 l S q BT 1 0 0 1 30 41 Tm /F2 9 Tf (2 Centers for Disease Control and Prevention www.cdc.gov/pcd/issues/2018/17_0389.htm)Tj ET Q " endstream endobj 3 0 obj <>/XObject<>>>/Rotate 0/Thumb 28 0 R/Type/Page>> endobj 4 0 obj <>stream xVgq BT 30 786 Td ET Q BT 1 0 0 1 30 684 Tm /F3 11 Tf 0 0 0 rg (Covariates)Tj 0 g ET BT 1 0 0 1 30 670 Tm /F1 10 Tf 0 0 0 rg 0.3655 Tw 0.1462 Tc [(6HYHUDO)-36.55(FRYDULDWHV)-36.55(ZHUH)-36.55(LQFOXGHG)-36.55(LQ)-36.55(WKH)-36.55(DQDO\\VLV)-36.55(EDVHG)-36.55(RQ)-36.55()]TJ 0 g 0 0 0 rg (SUHYL)Tj 0 g 0 Tw 0 Tc 1 0 0 1 30 658 Tm 0 0 0 rg 0.32832 Tw 0.13133 Tc [(RXV)-32.83(VWXGLHV)-32.83( )]TJ 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg [(\f)-32.83(VXFK)-32.83(DV)-32.83(VH[)-32.83( PDOH)-32.83(RU)-32.83(IHPDOH\f)-32.83(UDFHHWKQLFLW\\)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 646 Tm 0 0 0 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[(LYH)-14.2(XVHUV)-14.2(RI)-14.2(PHQWKRO)-14.2(FLJDUHWWHV)-14.2(+LJK)-14.2(VFKRRO)-14.2(FXUUHQW)-14.2(WREDFFR)-14.2(XVHUV)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 477 Tm 0 0 0 rg 0.07132 Tw 0.02853 Tc [(ZHUH)-7.13(PRUH)-7.13(OLNHO\\)-7.13(WKDQ)-7.13(PLGGOH)-7.13(VFKRRO)-7.13(XVHUV)-7.13(WR)-7.13(EH)-7.13(GXDO)-7.13(RU)-7.13(SRO\\)-7.13(XVHUV)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 465 Tm 0 0 0 rg (RIIODYRUHGSURGXFWV )Tj 0 g 1 0 0.21256 1 116.87 465 Tm 0 0 0 rg (3)Tj 0 g 1 0 0 1 122.43 465 Tm 0 0 0 rg (\f)Tj 0 g -92.43 0 Td ET BT 1 0 0 1 30 445 Tm /F1 10 Tf 0 0 0 rg 0.54012 Tw 0.21605 Tc [(2YHUDOO)-54.01(D)-54.01(VPDOOHU)-54.01(SHUFHQWDJH)-54.01(RI)-54.01(\\RXQJHU)-54.01(FXUUHQW)-54.01(WREDFFR)-54.01(XVHUV)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 433 Tm 0 0 0 rg 0.23174 Tw 0.0927 Tc [( )-23.17(\\HDUV)-23.17(ROG\f)-23.17(WKDQ)-23.17(ROGHU)-23.17(WREDFFR)-23.17(XVHUV)-23.17( !)-23.17(\\HDUV)-23.17(ROG\f)-23.17(UHSRUWHG)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 421 Tm 0 0 0 rg 0.0016 Tw 0.00064 Tc [(IODYRUHG)-0.15961(WREDFFR)-0.15961(XVH)-0.15961( \b)-0.15961(YV)-0.15961(\b)-0.15961()]TJ 0 g 1 0 0.21256 1 189.08 421 Tm 0 0 0 rg (3)Tj 0 g 1 0 0 1 194.64 421 Tm 0 0 0 rg [-0.15961()-0.15961(\f)-0.15961( )]TJ 0 g 0 0 0 rg [(7DEOH)-0.15961()]TJ 0 g 0 0 0 rg [(\f)-0.15961($)-0.15961()]TJ 0 g 0 0 0 rg (VLP)Tj 0 g 0 Tw 0 Tc -164.64 0 Td 1 0 0 1 30 409 Tm 0 0 0 rg 0.34408 Tw 0.13763 Tc [(LODU)-34.41(SURSRUWLRQ)-34.41(RI)-34.41(PDOH)-34.41(DQG)-34.41(IHPDOH)-34.41(FXUUHQW)-34.41(WREDFFR)-34.41(XVHUV)-34.41( \b)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 397 Tm 0 0 0 rg 0.19208 Tw 0.07683 Tc [(YV)-19.21(\b)-19.21()]TJ 0 g 1 0 0.21256 1 75.95 397 Tm 0 0 0 rg (3)Tj 0 g 1 0 0 1 81.59 397 Tm 0 0 0 rg [-19.21( )-19.21(\f)-19.21(UHSRUWHG)-19.21(IODYRUHG)-19.21(WREDFFR)-19.21(XVH)-19.21($)-19.21(VPDOOHU)-19.21()]TJ 0 g 0 0 0 rg (SUR)Tj 0 g 0 Tw 0 Tc -51.59 0 Td 1 0 0 1 30 385 Tm 0 0 0 rg 0.2991 Tw 0.11964 Tc [(SRUWLRQ)-29.91(RI)]TJ 0 g 0 0 0 rg [-29.91(QRQ+LVSDQLF)]TJ 0 g 0 0 0 rg [-29.91(EODFN)-29.91(FXUUHQW)-29.91(WREDFFR)-29.91(XVHUV)-29.91(UHSRUWHG)-29.91()]TJ 0 g 0 0 0 rg (XV)Tj 0 g 0 Tw 0 Tc 1 0 0 1 30 373 Tm 0 0 0 rg 0.05943 Tw 0.02377 Tc [(LQJ)-5.94(IODYRUHG)-5.94(WREDFFR)-5.94(SURGXFWV)-5.94(FRPSDUHG)-5.94(ZLWK)]TJ 0 g 0 0 0 rg [-5.94(QRQ+LVSDQLF)]TJ 0 g 0 0 0 rg [-5.94(ZKLWHV)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 361 Tm 0 0 0 rg ( \bYV\b)Tj 0 g 1 0 0.21256 1 103.88 361 Tm 0 0 0 rg (3)Tj 0 g 1 0 0 1 109.44 361 Tm 0 0 0 rg (\f)Tj 0 g -79.44 0 Td ET q 0.5 w 0.75294 0.75294 0.75294 RG 30 336 m 298 336 l S Q BT 1 0 0 1 30 341 Tm /F5 12 Tf 0 0 0 rg (\)DFWRUVDVVRFLDWHGZLWKIODYRUHGSURGXFWXVH)Tj 0 g /F2 12 Tf ()Tj ET BT 1 0 0 1 30 322 Tm /F1 10 Tf 0 0 0 rg 0.01919 Tw 0.00768 Tc [(%R\\V)-1.92(KDG)-1.92(KLJKHU)-1.92(RGGV)-1.92(RI)-1.92(UHSRUWLQJ)-1.92(FXUUHQW)-1.92(XVH)-1.92(RI)-1.92(ERWK)-1.92(IODYRUHG)-1.92(DQG)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 310 Tm 0 0 0 rg 0.04514 Tw 0.01806 Tc [(QRQIODYRUHG)-4.51(WREDFFR)-4.51(SURGXFWV)-4.51(WKDQ)-4.51(JLUOV)-4.51( )]TJ 0 g 0 0 0 rg [(7DEOH)-4.51()]TJ 0 g 0 0 0 rg [(\f)-4.51(+LJK)-4.51(VFKRRO)-4.51( YV)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 298 Tm 0 0 0 rg 0.18042 Tw 0.07217 Tc [(PLGGOH)-18.04(VFKRRO\f)-18.04(VWXGHQWV)-18.04(KDG)-18.04(KLJKHU)-18.04(RGGV)-18.04(RI)-18.04(UHSRUWLQJ)-18.04(QRQIODYRUHG)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 286 Tm 0 0 0 rg 0.12922 Tw 0.05169 Tc [(SURGXFW)-12.92(XVH)-12.92( $25)-12.92()-12.92(\b)-12.92(&,)-12.92(\f)-12.92(VLQJOH)]TJ 0 g 0 0 0 rg [-12.92(IODYRUHGSURGXFW)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 274 Tm 0 0 0 rg 0.91428 Tw 0.36571 Tc [(XVH)-91.43( $25)-91.43()-91.43(\b)-91.43(&,)-91.43(\f)-91.43(GXDO)]TJ 0 g 0 0 0 rg [-91.43(IODYRUHGSURGXFW)]TJ 0 g 0 0 0 rg [-91.43(XVH)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 262 Tm 0 0 0 rg 0.85974 Tw 0.3439 Tc [( $25)-85.97()-85.97(\b)-85.97(&,)-85.97(\f)-85.97(DQG)-85.97(SRO\\)]TJ 0 g 0 0 0 rg [-85.97(IODYRUHGSURGXFW)]TJ 0 g 0 0 0 rg [-85.97(XVH)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 250 Tm 0 0 0 rg 0.56442 Tw 0.22577 Tc [( $25)-56.44()-56.44(\b)-56.44(&,)-56.44(\f)]TJ 0 g 0 0 0 rg [-56.44(1RQ+LVSDQLF)]TJ 0 g 0 0 0 rg [-56.44(EODFNV)-56.44(DQG)-56.44(RWKHU)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 238 Tm 0 0 0 rg 0.425 Tw 0.17 Tc [(UDFHV)-42.5(ZHUH)-42.5(OHVV)-42.5(OLNHO\\)-42.5(WKDQ)]TJ 0 g 0 0 0 rg [-42.5(QRQ+LVSDQLF)]TJ 0 g 0 0 0 rg [-42.5(ZKLWHV)-42.5(WR)-42.5(UHSRUW)-42.5(XVH)-42.5(RI)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 226 Tm 0 0 0 rg 0.32861 Tw 0.13145 Tc [(IODYRUHG)-32.86(SURGXFWV)-32.86(EXW)-32.86(QRW)-32.86(QRQIODYRUHG)-32.86(SURGXFWV)-32.86(ZKLOH)-32.86(+LVSDQLFV)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 214 Tm 0 0 0 rg 0.33305 Tw 0.13322 Tc [(ZHUH)-33.3(PRUH)-33.3(OLNHO\\)-33.3(WKDQ)]TJ 0 g 0 0 0 rg [-33.3(QRQ+LVSDQLF)]TJ 0 g 0 0 0 rg [-33.3(ZKLWHV)-33.3(WR)-33.3(UHSRUW)-33.3(XVH)-33.3(RI)-33.3()]TJ 0 g 0 0 0 rg (QRQ)Tj 0 g 0 Tw 0 Tc 1 0 0 1 30 202 Tm 0 0 0 rg (IODYRUHGDQGVLQJOHIODYRUHGSURGXFWV)Tj 0 g ET BT 1 0 0 1 30 182 Tm /F1 10 Tf 0 0 0 rg 0.31566 Tw 0.12626 Tc [(+RXVHKROG)-31.57(WREDFFR)-31.57(XVH)-31.57(SDWWHUQV)-31.57( VLQJOH)-31.57(GXDO)-31.57(DQG)-31.57(SRO\\)]TJ 0 g 0 0 0 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[(PDJD]LQHV)-57.12(ZDV)-57.12(DVVRFLDWHG)-57.12(ZLWK)-57.12(KLJKHU)-57.12(RGGV)-57.12(RI)-57.12(VLQJOH)]TJ 0 g 0 0 0 rg [-57.12(IODYRUHG)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 110 Tm 0 0 0 rg 0.85063 Tw 0.34025 Tc (SURGXFW)Tj 0 g 0 0 0 rg [-85.06(XVH)-85.06( $25)-85.06()-85.06(\b)-85.06(&,)-85.06(\f)-85.06(DQG)-85.06(GXDO)]TJ 0 g 0 0 0 rg [-85.06(IODYRUHG)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 30 98 Tm 0 0 0 rg 0.04347 Tw 0.01739 Tc (SURGXFW)Tj 0 g 0 0 0 rg [-4.35(XVH)-4.35( $25)-4.35()-4.35(\b)-4.35(&,)-4.35(\f)-4.35(ZKLOH)-4.35(PRUH)-4.35(IUHTXHQW)-4.35()]TJ 0 g 0 0 0 rg (H[)Tj 0 g 0 Tw 0 Tc ET BT 1 0 0 1 316 684 Tm /F1 10 Tf 0 0 0 rg 0.53055 Tw 0.21222 Tc [(SRVXUH)-53.06(WR)-53.06(WREDFFR)-53.06(DGYHUWLVHPHQWV)-53.06(LQ)-53.06(VWRUHV)-53.06(ZDV)-53.06(DVVRFLDWHG)-53.06(ZLWK)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 672 Tm 0 0 0 rg 0.71615 Tw 0.28646 Tc [(KLJKHU)-71.61(RGGV)-71.61(RI)-71.61(GXDO)]TJ 0 g 0 0 0 rg [-71.61(IODYRUHGSURGXFW)]TJ 0 g 0 0 0 rg [-71.61(XVH)-71.61( $25)-71.61()-71.61(\b)-71.61(&,)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 660 Tm 0 0 0 rg 0.98618 Tw 0.39447 Tc [(\f)-98.62(DQG)-98.62(SRO\\)]TJ 0 g 0 0 0 rg [-98.62(IODYRUHGSURGXFW)]TJ 0 g 0 0 0 rg [-98.62(XVH)-98.62( $25)-98.62()-98.62(\b)-98.62(&,)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 648 Tm 0 0 0 rg (\f)Tj 0 g ET BT 1 0 0 1 316 624 Tm /F1 16 Tf 0 0 0 rg ('LVFXVVLRQ)Tj 0 g ET BT 1 0 0 1 316 602 Tm /F1 10 Tf 0 0 0 rg 0.43743 Tw 0.17497 Tc [(3DVW)-43.74(VWXGLHV)-43.74( )]TJ 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg [(\f)-43.74(KDYH)-43.74(HYDOXDWHG)-43.74(VLQJOH)-43.74(XVH)-43.74(RI)-43.74(IODYRUHG)-43.74(WREDFFR)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 590 Tm 0 0 0 rg 0.78694 Tw 0.31478 Tc [(SURGXFWV)-78.69(DQG)-78.69(LGHQWLILHG)-78.69(WKDW)-78.69(IODYRUHG)]TJ 0 g 0 0 0 rg [-78.69(HFLJDUHWWH)]TJ 0 g 0 0 0 rg [-78.69(XVDJH)-78.69(VXUJHV)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 578 Tm 0 0 0 rg 0.44494 Tw 0.17797 Tc [(DPRQJ)-44.49(\\RXWKV)-44.49(%XW)-44.49(SUHYLRXV)-44.49(VWXGLHV)-44.49(KDYH)-44.49(QRW)-44.49(H[DPLQHG)-44.49()]TJ 0 g 0 0 0 rg (FRQFXU)Tj 0 g 0 Tw 0 Tc 1 0 0 1 316 566 Tm 0 0 0 rg 0.0452 Tw 0.01808 Tc [(UHQW)-4.52(XVH)-4.52(RI)-4.52(YDULRXV)-4.52(IODYRUHG)-4.52(WREDFFR)-4.52(SURGXFWV)-4.52(9DULRXV)-4.52(IODYRUHG)-4.52()]TJ 0 g 0 0 0 rg (WR)Tj 0 g 0 Tw 0 Tc 1 0 0 1 316 554 Tm 0 0 0 rg 0.21722 Tw 0.08689 Tc [(EDFFR)-21.72(SURGXFWV)-21.72(DUH)-21.72(DYDLODEOH)-21.72(LQ)-21.72(WKH)-21.72(PDUNHW)-21.72( )]TJ 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg [(\f)-21.72(DQG)-21.72(QLFRWLQH)-21.72(OHYHOV)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 542 Tm 0 0 0 rg 0.37733 Tw 0.15093 Tc [(YDU\\)-37.73(VXEVWDQWLDOO\\)-37.73(DFURVV)-37.73(WKHVH)-37.73(SURGXFWV)-37.73(6WXGLHV)-37.73(KDYH)-37.73(VXJJHVWHG)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 530 Tm 0 0 0 rg 0.07222 Tw 0.02889 Tc [(WKDW)-7.22(WREDFFR)-7.22(FRPSDQLHV)-7.22(PD\\)-7.22(XVH)-7.22(IODYRUHG)-7.22(SURGXFWV)-7.22(ZLWK)-7.22(ORZ)-7.22()]TJ 0 g 0 0 0 rg (QLFRW)Tj 0 g 0 Tw 0 Tc 1 0 0 1 316 518 Tm 0 0 0 rg 0.30706 Tw 0.12283 Tc [(LQH)-30.71(OHYHOV)-30.71(WR)-30.71(OXUH)-30.71(QHZ)-30.71(XVHUV)-30.71( )]TJ 0 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0.15 Tc /F7 8 Tf 2 Tr 0.26667 w 0 0 0 RG 0 0 0 rg (,QFOXGLQJ)Tj 0 g 0 Tr 0 G 1 w 0 Tc 1 0 0 1 466.54 634 Tm 0.15 Tc 2 Tr 0.26667 w 0 0 0 RG 0 0 0 rg (\(FLJDUHWWHV)Tj 0 g 0 Tr 0 G 1 w 0 Tc ET BT 1 0 0 1 528.32 642 Tm 0.15 Tc /F7 8 Tf 2 Tr 0.26667 w 0 0 0 RG 0 0 0 rg (1RW,QFOXGLQJ)Tj 0 g 0 Tr 0 G 1 w 0 Tc 1 0 0 1 530.8 634 Tm 0.15 Tc 2 Tr 0.26667 w 0 0 0 RG 0 0 0 rg (\(FLJDUHWWHV)Tj 0 g 0 Tr 0 G 1 w 0 Tc ET BT 1 0 0 1 32 619 Tm /F7 8 Tf 2 Tr 0.26667 w 0 0 0 RG 0 0 0 rg (8QZHLJKWHG1)Tj 0 g 0 Tr 0 G 1 w ET BT 1 0 0 1 164.92 619 Tm /F7 8 Tf 0 0 0 rg ()Tj 0 g ET BT 1 0 0 1 238.56 619 Tm /F7 8 Tf 0 0 0 rg ()Tj 0 g ET BT 1 0 0 1 298.83 619 Tm /F7 8 Tf 0 0 0 rg ()Tj 0 g ET BT 1 0 0 1 372.47 619 Tm /F7 8 Tf 0 0 0 rg ()Tj 0 g ET BT 1 0 0 1 439.43 619 Tm /F7 8 Tf 0 0 0 rg ()Tj 0 g ET BT 1 0 0 1 500.98 619 Tm /F7 8 Tf 0 0 0 rg ()Tj 0 g ET BT 1 0 0 1 572.62 619 Tm /F7 8 Tf 0 0 0 rg ()Tj 0 g ET BT 1 0 0 1 32 605 Tm /F7 8 Tf 2 Tr 0.26667 w 0 0 0 RG 0 0 0 rg (:HLJKWHG1 LQV\f)Tj 0 g 0 Tr 0 G 1 w ET BT 1 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