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40.91 55.35 41.74 56.32 43.43 c 56.82 42.74 57.06 41.61 56.67 40.78 c f 37.18 21.92 m 38.99 21.15 40.88 20.39 42.5 19.33 c 42.9 19 43.26 18.51 43.19 17.91 c 42.63 15.62 39.44 15.38 39.91 12.68 c 40.05 11.67 40.71 10.79 41.7 10.52 c 42.14 10.39 42.74 10.39 43.19 10.52 c 43.26 10.34 43.57 10.17 43.22 10.05 c 41.91 9.22 40.23 8.28 38.64 9.08 c 37.86 9.44 37.4 10.28 37.2 11.1 c 36.87 13.54 39.16 14.31 40.31 15.95 c 40.48 16.28 40.57 16.66 40.48 17.05 c 40.26 17.51 39.94 17.79 39.5 18.06 c 35.21 20.46 30.54 22.09 25.74 23.33 c 24.95 23.41 23.71 23.87 23.18 22.95 c 23.18 22.9 l 22.76 22.82 22.92 23.33 22.92 23.56 c 23.05 24.34 23.51 24.97 24.24 25.29 c 25.49 25.66 26.81 25.22 28.02 25 c 31.12 24.13 34.21 23.15 37.18 21.92 c f 35.31 11.7 m 35.3 11.84 35.28 11.85 35.05 11.85 c 34.37 11.84 34.09 11.52 34.11 10.75 c 34.13 9.97 34.41 9.68 35.09 9.7 c 35.32 9.7 35.35 9.72 35.35 9.79 c 35.31 11.7 l h 36.15 11.9 m 35.76 11.86 35.75 11.85 35.73 11.75 c 35.72 11.63 35.72 11.35 35.74 10.8 c 35.75 10.25 35.75 9.97 35.77 9.84 c 35.79 9.75 35.81 9.74 36.19 9.72 c 36.19 9.57 l 34.98 9.55 l 34.48 9.53 34.24 9.64 34.01 9.85 c 33.8 10.04 33.65 10.35 33.64 10.75 c 33.63 11.37 34.01 12 34.98 12.02 c 36.14 12.04 l 36.15 11.9 l h f 33.42 11.86 m 33.09 11.86 33.07 11.85 33.05 11.75 c 33.03 11.63 33 11.35 32.96 10.8 c 32.91 10.25 32.89 9.97 32.89 9.85 c 32.89 9.75 32.91 9.74 33.24 9.69 c 33.22 9.54 l 31.89 9.65 l 31.69 9.67 31.49 9.67 31.34 9.65 c 31.35 9.83 31.35 10.23 31.33 10.33 c 31.49 10.34 l 31.55 9.88 31.62 9.82 32.11 9.78 c 32.43 9.76 l 32.47 9.75 32.49 9.77 32.5 9.82 c 32.57 10.63 l 32.57 10.67 32.56 10.69 32.46 10.7 c 32.36 10.71 l 31.97 10.75 31.94 10.68 31.89 10.44 c 31.73 10.45 l 31.75 10.56 31.77 10.68 31.78 10.85 c 31.79 10.99 31.79 11.15 31.8 11.25 c 31.96 11.24 l 31.96 10.98 32 10.91 32.28 10.89 c 32.52 10.87 l 32.56 10.87 32.59 10.88 32.59 10.93 c 32.67 11.83 l 32.68 11.88 32.65 11.9 32.61 11.9 c 32.01 11.95 l 31.72 11.98 31.64 11.9 31.55 11.68 c 31.45 11.44 l 31.29 11.5 l 31.36 11.69 31.43 12.02 31.44 12.18 c 33.43 12.01 l 33.42 11.86 l h f 30.12 11.06 m 30.06 11.08 30.01 11.09 29.95 11.1 c 29.6 11.17 29.27 11.16 29.18 10.7 c 29.1 10.26 29.37 10.15 29.76 10.08 c 29.92 10.05 29.93 10.06 29.95 10.13 c 30.12 11.06 l h 31.14 12.05 m 30.78 12.09 30.76 12.09 30.72 12 c 30.69 11.88 30.63 11.6 30.54 11.06 c 30.44 10.52 30.38 10.24 30.38 10.12 c 30.38 10.02 30.39 10.01 30.74 9.91 c 30.72 9.77 l 29.43 10 l 29.17 10.05 28.98 10.16 28.85 10.31 c 28.74 10.44 28.7 10.6 28.73 10.79 c 28.82 11.28 29.28 11.4 29.91 11.29 c 30 11.27 30.1 11.24 30.15 11.24 c 30.3 12.07 l 30.32 12.17 30.29 12.18 29.89 12.29 c 29.92 12.43 l 31.16 12.2 l 31.14 12.05 l h f 27.54 11.96 m 27.51 11.97 27.5 11.96 27.49 11.95 c 27.49 11.94 27.49 11.89 27.49 11.87 c 27.58 10.92 l 28.16 11.7 l 28.18 11.72 28.19 11.74 28.2 11.75 c 28.2 11.77 28.19 11.78 28.16 11.79 c 27.54 11.96 l h 29.24 12.38 m 28.96 12.44 28.9 12.37 28.7 12.11 c 27.7 10.79 l 27.53 10.57 27.49 10.51 27.41 10.4 c 27.23 10.45 l 27.24 10.56 27.23 10.77 27.22 10.89 c 27.01 12.73 l 26.98 12.98 26.97 13.02 26.68 13.1 c 26.72 13.25 l 27.89 12.92 l 27.85 12.78 l 27.5 12.86 27.46 12.83 27.44 12.75 c 27.42 12.68 27.46 12.25 27.47 12.21 c 27.47 12.19 27.49 12.18 27.5 12.17 c 27.59 12.14 27.76 12.08 28.1 11.98 c 28.32 11.92 28.33 11.94 28.38 12 c 28.53 12.18 28.63 12.35 28.64 12.39 c 28.67 12.49 28.64 12.52 28.32 12.65 c 28.36 12.79 l 29.28 12.52 l 29.24 12.38 l h f 25.39 12.27 m 25.41 12.33 25.41 12.35 25.21 12.43 c 24.72 12.63 24.51 12.39 24.44 12.21 c 24.33 11.94 24.45 11.67 24.8 11.52 c 25.03 11.43 25.04 11.43 25.08 11.52 c 25.39 12.27 l h 26.6 13.13 m 26.27 13.25 26.25 13.24 26.2 13.16 c 26.14 13.05 26.03 12.79 25.82 12.28 c 25.61 11.77 25.51 11.51 25.48 11.39 c 25.45 11.3 25.46 11.28 25.77 11.12 c 25.72 10.98 l 24.5 11.48 l 24.25 11.58 24.13 11.67 24.04 11.82 c 23.94 11.96 23.93 12.14 24.01 12.33 c 24.21 12.82 24.77 12.69 24.78 12.72 c 24.78 12.73 24.78 12.76 24.77 12.82 c 24.54 13.74 l 24.48 13.97 24.46 14.01 24.3 14.08 c 24.36 14.22 l 24.9 13.99 l 25.18 12.68 l 25.19 12.63 25.21 12.61 25.35 12.56 c 25.48 12.51 25.49 12.51 25.5 12.54 c 25.74 13.13 25.78 13.23 25.8 13.32 c 25.83 13.41 25.82 13.43 25.51 13.59 c 25.57 13.73 l 26.66 13.28 l 26.6 13.13 l h f 24.09 14.21 m 23.74 14.36 23.72 14.36 23.66 14.28 c 23.62 14.22 23.56 14.11 23.46 13.93 c 22.71 12.48 l 23.07 12.29 l 23.18 12.23 23.27 12.3 23.59 12.6 c 23.72 12.49 l 23.62 12.38 23.51 12.22 23.35 11.93 c 23.29 11.98 23.24 12.01 23.17 12.05 c 23.12 12.09 23.06 12.13 23 12.16 c 21.91 12.72 l 21.78 12.79 21.65 12.84 21.53 12.88 c 21.66 13.18 21.74 13.36 21.77 13.51 c 21.94 13.46 l 21.87 13.03 21.87 12.91 21.98 12.86 c 22.34 12.67 l 23.1 14.12 l 23.19 14.3 23.25 14.42 23.27 14.49 c 23.3 14.58 23.29 14.6 22.97 14.79 c 23.03 14.93 l 24.16 14.34 l 24.09 14.21 l h f 22.47 15.02 m 22.14 15.22 22.11 15.22 22.05 15.15 c 21.97 15.05 21.81 14.82 21.5 14.37 c 21.19 13.92 21.03 13.68 20.97 13.57 c 20.93 13.48 20.94 13.46 21.24 13.23 c 21.16 13.1 l 20.37 13.64 l 20.38 13.66 20.4 13.7 20.41 13.74 c 20.92 15.63 l 20.91 15.63 l 19.23 14.42 l 18.45 14.95 l 18.54 15.08 l 18.87 14.88 18.89 14.87 18.95 14.95 c 19.03 15.04 19.2 15.28 19.5 15.73 c 19.81 16.18 19.98 16.42 20.03 16.53 c 20.08 16.61 20.07 16.63 19.77 16.87 c 19.85 16.99 l 20.87 16.3 l 20.79 16.17 l 20.47 16.36 20.43 16.36 20.39 16.29 c 19.27 14.66 l 19.27 14.66 l 21.01 15.91 l 21.06 15.95 21.11 15.98 21.16 16.03 c 21.38 15.87 l 21.37 15.85 21.34 15.79 21.33 15.73 c 20.77 13.63 l 20.77 13.63 l 21.71 14.99 l 21.77 15.08 21.84 15.22 21.86 15.28 c 21.91 15.36 21.9 15.38 21.63 15.6 c 21.71 15.72 l 22.56 15.15 l 22.47 15.02 l h f 19.73 16.94 m 19.47 17.14 19.44 17.14 19.37 17.08 c 19.28 16.99 19.1 16.78 18.73 16.37 c 18.37 15.95 18.18 15.74 18.12 15.64 c 18.06 15.56 18.07 15.54 18.3 15.3 c 18.2 15.19 l 17.2 16.07 l 17.04 16.2 16.87 16.32 16.75 16.4 c 16.86 16.53 17.1 16.86 17.14 16.95 c 17.28 16.87 l 17.05 16.46 17.07 16.37 17.45 16.04 c 17.69 15.84 l 17.72 15.81 17.75 15.81 17.78 15.84 c 18.31 16.45 l 18.35 16.49 18.35 16.51 18.27 16.58 c 18.2 16.65 l 17.91 16.9 17.85 16.87 17.66 16.7 c 17.54 16.81 l 17.62 16.89 17.69 16.97 17.81 17.1 c 17.91 17.21 18 17.33 18.07 17.41 c 18.19 17.31 l 18.03 17.1 18.03 17.02 18.24 16.84 c 18.42 16.68 l 18.45 16.65 18.48 16.65 18.51 16.68 c 19.11 17.36 l 19.14 17.4 19.14 17.43 19.1 17.46 c 18.65 17.86 l 18.43 18.05 18.32 18.04 18.12 17.91 c 17.91 17.77 l 17.81 17.92 l 17.97 18.03 18.22 18.26 18.33 18.37 c 19.83 17.06 l 19.73 16.94 l h f 18.03 18.42 m 17.78 18.66 17.75 18.66 17.68 18.61 c 17.58 18.53 17.37 18.34 16.96 17.97 c 16.56 17.59 16.35 17.4 16.27 17.31 c 16.21 17.23 16.22 17.21 16.43 16.94 c 16.32 16.84 l 15.82 17.38 l 15.84 17.42 15.85 17.48 15.87 17.56 c 16.31 19.49 l 16.3 19.49 l 15.9 19.11 l 15.5 18.74 15.29 18.55 15.21 18.45 c 15.14 18.38 15.15 18.35 15.39 18.06 c 15.28 17.95 l 14.6 18.69 l 14.71 18.79 l 14.93 18.55 14.97 18.54 15.12 18.66 c 15.26 18.79 15.43 18.93 15.57 19.06 c 16.08 19.53 16.5 19.93 16.69 20.14 c 16.86 19.95 l 16.76 19.65 16.7 19.42 16.63 19.1 c 16.31 17.61 l 16.31 17.61 l 16.84 18.1 l 17.24 18.47 17.45 18.66 17.53 18.76 c 17.59 18.84 17.59 18.86 17.31 19.19 c 17.42 19.29 l 18.14 18.52 l 18.03 18.42 l h f 15.94 20.77 m 15.68 21.06 15.66 21.07 15.58 21.03 c 15.52 20.99 15.41 20.91 15.25 20.79 c 13.94 19.81 l 14.18 19.48 l 14.25 19.39 14.36 19.41 14.78 19.54 c 14.86 19.39 l 14.72 19.33 14.55 19.23 14.28 19.04 c 14.24 19.11 14.21 19.17 14.17 19.23 c 14.14 19.28 14.1 19.34 14.06 19.4 c 13.33 20.37 l 13.23 20.5 13.14 20.6 13.04 20.69 c 13.3 20.89 13.45 21.03 13.54 21.14 c 13.66 21.03 l 13.42 20.67 13.37 20.57 13.44 20.47 c 13.68 20.14 l 15 21.12 l 15.16 21.25 15.26 21.33 15.31 21.38 c 15.38 21.44 15.38 21.47 15.17 21.79 c 15.29 21.88 l 16.05 20.86 l 15.94 20.77 l h f 13.63 24.38 m 13.46 24.72 12.98 24.83 12.31 24.48 c 11.64 24.12 11.47 23.66 11.65 23.33 c 11.82 22.99 12.3 22.88 12.97 23.23 c 13.64 23.58 13.81 24.04 13.63 24.38 c 11.49 23.25 m 11.19 23.83 11.41 24.52 12.1 24.88 c 12.78 25.24 13.47 25.04 13.78 24.46 c 14.09 23.88 13.87 23.18 13.18 22.82 c 12.5 22.46 11.8 22.66 11.49 23.25 c f 12.96 25.62 m 12.81 25.91 12.8 25.92 12.7 25.9 c 12.58 25.87 12.32 25.76 11.82 25.55 c 11.3 25.35 11.04 25.24 10.93 25.18 c 10.84 25.13 10.84 25.12 10.94 24.8 c 10.81 24.75 l 10.3 25.98 l 10.23 26.17 10.13 26.36 10.06 26.48 c 10.21 26.54 10.58 26.73 10.66 26.79 c 10.74 26.66 l 10.35 26.39 10.34 26.31 10.52 25.85 c 10.64 25.55 l 10.66 25.51 10.68 25.5 10.73 25.52 c 11.48 25.82 l 11.52 25.84 11.54 25.86 11.5 25.95 c 11.46 26.05 l 11.31 26.4 11.25 26.4 11 26.34 c 10.95 26.49 l 11.05 26.53 11.16 26.56 11.32 26.63 c 11.46 26.68 11.6 26.74 11.69 26.78 c 11.75 26.64 l 11.52 26.52 11.48 26.45 11.58 26.2 c 11.68 25.97 l 11.69 25.93 11.71 25.92 11.76 25.94 c 12.56 26.26 l 12.65 26.29 12.64 26.32 12.52 26.7 c 12.66 26.76 l 13.1 25.67 l 12.96 25.62 l h f 11.83 28.59 m 11.72 28.94 11.7 28.96 11.6 28.95 c 11.49 28.93 11.21 28.87 10.67 28.74 c 10.14 28.62 9.87 28.55 9.75 28.51 c 9.65 28.48 9.65 28.45 9.71 28.1 c 9.56 28.07 l 9.28 29.26 l 9.43 29.3 l 9.53 28.94 9.55 28.93 9.65 28.94 c 9.72 28.95 9.93 28.99 10.1 29.03 c 10.32 29.09 l 10.43 29.11 10.44 29.12 10.42 29.21 c 10.21 30.12 l 10.18 30.21 10.17 30.22 10.07 30.19 c 9.83 30.14 l 9.67 30.1 9.46 30.05 9.39 30.03 c 9.3 29.99 9.29 29.97 9.35 29.61 c 9.21 29.58 l 8.92 30.77 l 9.07 30.81 l 9.18 30.46 9.19 30.44 9.29 30.45 c 9.41 30.47 9.69 30.53 10.22 30.66 c 10.76 30.79 11.03 30.85 11.15 30.89 c 11.24 30.92 11.25 30.95 11.19 31.3 c 11.34 31.34 l 11.62 30.14 l 11.47 30.11 l 11.36 30.45 11.35 30.47 11.25 30.46 c 11.15 30.45 10.87 30.39 10.46 30.29 c 10.36 30.27 10.35 30.26 10.37 30.16 c 10.58 29.26 l 10.6 29.16 10.62 29.16 10.72 29.18 c 11.13 29.27 11.41 29.34 11.5 29.38 c 11.6 29.41 11.6 29.43 11.54 29.79 c 11.69 29.83 l 11.97 28.63 l 11.83 28.59 l h f 11.19 31.42 m 11.12 31.75 11.11 31.76 11.01 31.76 c 10.89 31.76 10.61 31.73 10.06 31.66 c 9.52 31.59 9.23 31.56 9.12 31.53 c 9.02 31.51 9.01 31.49 9.03 31.16 c 8.88 31.14 l 8.71 32.47 l 8.69 32.67 8.65 32.87 8.61 33.01 c 8.78 33.04 9.18 33.12 9.27 33.15 c 9.32 33.01 l 8.87 32.85 8.83 32.78 8.89 32.28 c 8.93 31.96 l 8.93 31.92 8.96 31.91 9.01 31.91 c 9.81 32.01 l 9.87 32.01 9.87 32.02 9.87 32.13 c 9.85 32.23 l 9.8 32.61 9.74 32.63 9.48 32.63 c 9.47 32.78 l 9.59 32.8 9.69 32.8 9.87 32.82 c 10.01 32.84 10.17 32.87 10.27 32.88 c 10.28 32.73 l 10.03 32.67 9.98 32.61 10.01 32.34 c 10.04 32.1 l 10.04 32.05 10.06 32.04 10.11 32.04 c 11 32.15 l 11.05 32.16 11.07 32.18 11.07 32.22 c 11 32.82 l 10.96 33.11 10.88 33.17 10.64 33.22 c 10.39 33.26 l 10.41 33.43 l 10.61 33.41 10.95 33.41 11.1 33.42 c 11.34 31.44 l 11.19 31.42 l h f 10.02 35.1 m 10.02 35.13 10.01 35.15 10.01 35.15 c 9.98 35.15 9.95 35.13 9.92 35.12 c 9.04 34.77 l 9.96 34.43 l 9.98 34.42 10 34.41 10.02 34.41 c 10.03 34.41 10.04 34.43 10.04 34.45 c 10.02 35.1 l h 10.92 33.6 m 10.89 33.87 10.81 33.92 10.5 34.03 c 8.95 34.62 l 8.69 34.72 8.62 34.75 8.49 34.78 c 8.49 34.97 l 8.6 34.98 8.79 35.05 8.9 35.1 c 10.61 35.84 l 10.84 35.93 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659 Tm 0 Tw 0 Tc -268.22 0 Td 1 0 0 1 316 647 Tm 1 0 0.21256 1 316 647 Tm 0 0 0 rg 0.52849 Tw 0.2114 Tc (HODQWH)Tj 0 g 1 0 0 1 341.1 647 Tm 0 0 0 rg [-52.85(LQWHUYHQWLRQ)-52.85(LQ)-52.85('RXJODV)-52.85($UL]RQD)-52.85( Q)-52.85( )-52.85(\f)-52.85(ZH)-52.85(XVHG)-52.85(WKH)]TJ 0 g 0 Tw 0 Tc -25.1 0 Td 1 0 0 1 316 635 Tm 0 0 0 rg 0.63596 Tw 0.25438 Tc [(VDPH)-63.6(TXHVWLRQQDLUH)-63.6(DQG)-63.6(PHDVXUHPHQW)-63.6(SURWRFROV)-63.6(7KH)-63.6()]TJ 0 g 0 0 0 rg (TXHVWLRQ)Tj 0 g 0 Tw 0 Tc 1 0 0 1 316 623 Tm 0 0 0 rg 0.14651 Tw 0.0586 Tc [(QDLUH)-14.65(FRYHUHG)-14.65(SK\\VLFDO)-14.65(DFWLYLW\\)-14.65(HDWLQJ)-14.65(KDELWV)-14.65(SK\\VLFDO)-14.65(DQG)-14.65(PHQWDO)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 611 Tm 0 0 0 rg 0.07484 Tw 0.02994 Tc [(KHDOWK)-7.48(DQG)-7.48(VRFLRGHPRJUDSKLF)-7.48(LQIRUPDWLRQ)-7.48( 7KH)-7.48(ILQGLQJV)-7.48(RQ)-7.48()]TJ 0 g 0 0 0 rg (SK\\V)Tj 0 g 0 Tw 0 Tc 1 0 0 1 316 599 Tm 0 0 0 rg 0.52254 Tw 0.20902 Tc 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0 Tc 1 0 0 1 316 479 Tm 0 0 0 rg 0.33544 Tw 0.13418 Tc [(DGPLQLVWHU)-33.54(WKH)-33.54(OLIHVW\\OH)-33.54(TXHVWLRQQDLUH)-33.54(DQG)-33.54(FROOHFW)-33.54(DQWKURSRPHWULF)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 467 Tm 0 0 0 rg 0.29838 Tw 0.11935 Tc [(PHDVXUHPHQWV)-29.84($)-29.84(FHUWLILHG)-29.84(ODERUDWRU\\)-29.84(DQG)-29.84(SKOHERWRPLVW)-29.84(FROOHFWHG)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 455 Tm 0 0 0 rg (EORRGVDPSOHV)Tj 0 g ET q 0.5 w 0.75294 0.75294 0.75294 RG 316 430 m 584 430 l S Q BT 1 0 0 1 316 435 Tm /F5 12 Tf 0 0 0 rg (6WDWLVWLFDOPHWKRGV)Tj 0 g /F2 12 Tf ()Tj ET BT 1 0 0 1 316 416 Tm /F3 11 Tf 0 0 0 rg (Primary analysis)Tj 0 g ET BT 1 0 0 1 316 399 Tm /F1 10 Tf 0 0 0 rg 0.27286 Tw 0.10915 Tc [(:H)-27.29(FRPSDUHG)-27.29(WKH)-27.29(EDVHOLQH)-27.29(FKDUDFWHULVWLFV)-27.29(RI)-27.29(WKRVH)-27.29(ZLWK)-27.29(FRPSOHWH)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 387 Tm 0 0 0 rg 0.09703 Tw 0.03881 Tc 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Tc [(UDQGRP)-21.29(HIIHFW)-21.29(WR)-21.29(DFFRXQW)-21.29(IRU)]TJ 0 g 0 0 0 rg [-21.29(ZLWKLQSDUWLFLSDQW)]TJ 0 g 0 0 0 rg [-21.29(FRUUHODWLRQ)-21.29(GXH)-21.29(WR)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 327 Tm 0 0 0 rg 0.28689 Tw 0.11476 Tc [(UHSHDWHG)-28.69(PHDVXUHPHQWV)-28.69(7LPH)-28.69(ZDV)-28.69(XVHG)-28.69(DV)-28.69(D)-28.69(FDWHJRULFDO)-28.69(YDULDEOH)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 315 Tm 0 0 0 rg 0.29187 Tw 0.11675 Tc [(ZKLFK)-29.19(UHGXFHV)-29.19(WKH)-29.19(OLNHOLKRRG)-29.19(RI)-29.19(PRGHO)-29.19(PLVVSHFLILFDWLRQ)-29.19( )]TJ 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg [(\f)-29.19($OO)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 303 Tm 0 0 0 rg 0.1523 Tw 0.06092 Tc [(DYDLODEOH)-15.23(RXWFRPH)-15.23(GDWD)-15.23(ZHUH)-15.23(XVHG)-15.23(LQ)-15.23(WKH)-15.23(PL[HG)-15.23(PRGHOV)-15.23(ZKLFK)-15.23(DUH)]TJ 0 g 0 Tw 0 Tc 1 0 0 1 316 291 Tm 0 0 0 rg 0.50201 Tw 0.2008 Tc [(UREXVW)-50.2(LQ)-50.2(WKH)-50.2(SUHVHQFH)-50.2(RI)-50.2(PLVVLQJ)-50.2(GDWD)-50.2( )]TJ 0 g 0 0 0 rg ()Tj 0 g 0 0 0 rg 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Articles focus on preventing and controlling chronic diseases and conditions, promoting health, and examining the biological, behavioral, physical, and social determinants of health and their impact on quality of life, morbidity, and mortality across the life span. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. 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