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Homestyle Biscuits3.03.5General MillsOld Fashioned Kettle Corn Popcorn5.06.0General MillsReady to Bake Cookie Dough (Chocolate Chip)1.02.0General Mills Ready to Bake Cookie Dough (Sugar Cookie)1.52.0Giant BrandsCrescent Dinner Rolls1.52.0Giant BrandsGraham Cracker Pie Crust2.03.0Giant BrandsJumbos Buttermilk Biscuits2.03.0H.J Heinz CompanyTurkey Breast Medallions0.51.0On-Cor Frozen FoodsBreaded Veal Permagiana0.3*1.0Walmart StoresStick Margarine2.53.0 *Nutrition Facts panel listed product as containing 0.3g/serving of TFA. Product assumed to contain 0.5g/serving of TFA as food labeling regulation requires TFA content of foods be presented to the nearest 0.5g/serving. Supplementary Table 2. Average TFA content from 2007 to 2011 of brand-name U.S. supermarket food products that contained e"0.5 g/serving TFA in 2007, according to food categories. TFA content in g/serving by year*2007 2008 2010 2011 Breads (15)Mean (SD)1.7 0.70.6 0.80.3 0.60.5 0.8Median (IQR )! 2.0 (1.0, 2.0)0.3 (0.0, 1.0)0.0 (0.0, 0.3)0.0 (0.0, 1.0)Breakfasts (8)Mean (SD)1.5 0.91.1 0.9 0.8 1.00.8 1.0Median (IQR )1.8 (0.5, 2.0)1.0 (0.4, 1.5)0.4 (0.3, 1.0)0.4 (0.3, 1.0)Cakes and pastries (39)Mean (SD)1.8 1.31.1 1.00.8 0.90.7 0.7Median (IQR )1.5 (1.0, 2.0)1.0 (0.3, 1.5)0.3 (0.3, 1.5)0.3 (0.3, 1.5)Cookies, biscuits and bars (39)Mean (SD)1.9 1.01.2 1.11.2 1.21.1 1.1Median (IQR )1.5 (1.0, 2.5)1.0 (0.3, 1.5)1.0 (0.3, 2.0)1.0 (0.0, 2.0)Crackers (15)Mean (SD)2.3 1.31.4 1.30.4 0.50.4 0.5Median (IQR )2.0 (1.0, 3.5)1.0 (0.3, 2.0)0.0 (0.0, 1.0)0.0 (0.0, 1.0)Doughnuts (7)Mean (SD)3.1 1.80.3 0.00.3 0.00.3 0.0Median (IQR )4.0 (0.5, 4.0)0.3 (0.3, 0.3)0.3 (0.3, 0.3)0.3 (0.3, 0.3)French fries/other potatoes (18)Mean (SD)1.3 0.60.1 0.30.1 0.10.1 0.1Median (IQR )1.0 (0.5, 2.0)0.0 (0.0, 0.3)0.0 (0.0, 0.3)0.0 (0.0, 0.3)Ice creams (7)Mean (SD)1.4 1.30.3 0.30.3 0.30.2 0.2Median (IQR )1.0 (0.5, 2.0)0.3 (0.0, 0.5)0.3 (0.0, 0.5)0.3 (0.0, 0.3)Margarines (11)Mean (SD)2.0 0.62.0 0.51.7 0.91.6 0.8Median (IQR )2.0 (1.5, 2.5)2.0 (1.5, 2.5)2.0 (1.0, 2.5)1.5 (1.0, 2.5)Meats and seafood (41)Mean (SD)1.2 0.90.8 0.60.6 0.60.6 0.6Median (IQR )1.0 (0.5, 1.5)0.5 (0.5, 1.0)0.5 (0.3, 1.0)0.5 (0.0, 1.0)Muffins (5)Mean (SD)0.7 0.30.6 0.50.3 0.10.25 0.0Median (IQR )0.5 (0.5, 1.0)0.5 (0.3, 0.5)0.3 (0.3, 0.3)0.3 (0.3, 0.3)Pasta (10)Mean (SD)1.1 0.81.2 1.20.5 0.60.4 0.4Median (IQR )0.5 (0.5, 1.5)0.5 (0.5, 2.0)0.3 (0.0, 0.5)0.3 (0.0, 0.5)Pies (22)Mean (SD)3.2 1.12.6 1.41.7 1.61.7 1.6Median (IQR )3.0 (2.5, 4.0)2.5 (2.0, 3.5)1.8 (0.3, 3.0)1.8 (0.3, 3.0)Pizzas (12)Mean (SD)2.0 1.62.2 1.52.0 1.61.4 1.5Median (IQR )1.3 (0.8, 3.8)1.5 (1.0, 3.8)1.3 (1.0, 3.8)1.0 (0.3, 2.0)Popcorns (11)Mean (SD)4.5 1.34.2 1.83.8 2.13.8 2.2Median (IQR )4.5 (4.0, 6.0)4.5 (3.5, 6.0)4.5 (3.5, 6.0)4.0 (2.0, 6.0)Rolls (10)Mean (SD)1.9 0.61.6 1.01.6 0.81.6 0.8Median (IQR )2.0 (1.5, 2.5)1.8 (0.3, 2.5)1.8 (1.5, 2.0)1.8 (1.5, 2.0)* Data were not collected in 2009. All products listing 0g TFA but still containing partially hydrogenated oils in the ingredients list were considered to still contain 0.25g/serving of TFA. IQR=interquartile range (25th, 75th percentile). Supplementary Table 3. Average TFA content from 2007 to 2011 of 236 brand-name U.S. supermarket food products that contained e"0.5 g/serving TFA in 2007, by their major (>3 products) parent companies TFA content in g/serving by year*2007 2008 2010 2011 American Pies (4)Mean (SD)4.5 0.44.3 0.64.4 0.34.4 0.3Median (IQR)4.5 (4.3, 4.8)4.3 (3.8, 4.8)4.5 (4.3, 4.5)4.5 (4.3, 4.5)Campbell Soup (12)Mean (SD)2.3 1.62.1 1.70.8 1.10.8 0.9Median (IQR )2.0 (1.3, 3.3)1.5 (0.8, 3.3)0.1 (0.0, 1.5)0.3 (0.0, 1.8)Coles Quality Foods (4)Mean (SD)1.6 0.50.0 0.00.0 0.00.0 0.0Median (IQR )1.8 (1.3, 2.0)0.0 (0.0, 0.0)0.0 (0.0, 0.0)0.0 (0.0, 0.0)ConAgra Foods (14)Mean (SD)1.4 0.51.3 0.61.1 0.81.1 0.7Median (IQR )1.5(1.0, 1.5)1.3 (1.0, 1.5)1.3 (0.5, 1.5)1.3 (1.0, 1.5)Continental Mills (4)Mean (SD)1.1 0.61.1 0.60.6 0.90.5 0.7Median (IQR )1.0 (0.8, 1.5)1.0 (0.8, 1.5)0.3 (0.1, 1.1)0.3 (0.1, 0.9)General Mills (48)Mean (SD)1.9 1.01.7 1.21.6 1.21.4 1.1Median (IQR )1.8 (1.0, 2.3)1.5 (1.0, 2.0)1.5 (0.8, 2.0)1.5 (0.5, 2.0)Giant Brands (12)Mean (SD)2.4 1.82.5 1.82.2 2.02.4 2.0Median (IQR )2.0 (1.3, 2.5)2.3 (1.5, 2.8)2.0 (0.6, 2.8)2.0 (0.9, 3.0)H.J. Heinz (18)Mean (SD)1.3 0.60.4 0.50.4 0.50.5 0.6Median (IQR )1.0 (1.0, 2.0)0.3 (0.0, 0.5)0.3 (0.0, 0.5)0.3 (0.0, 1.0)Interstate Bakeries (13)Mean (SD)1.1 0.60.4 0.40.3 0.20.2 0.1Median (IQR )1.0 (0.5, 1.5)0.3 (0.3, 0.3)0.3 (0.3, 0.3)0.3 (0.3, 0.3)Kellogg Company(22)Mean (SD)2.3 1.40.9 1.30.3 0.50.3 0.5Median (IQR )2.0 (1.5, 3.0)0.3 (0.0, 1.5)0.0 (0.0, 0.3)0.0 (0.0, 0.3)Kraft Foods (8)Mean (SD)0.8 0.30.9 0.40.8 0.30.5 0.4Median (IQR )0.8 (0.5, 1.0)1.0 (0.5, 1.0)1.0 (0.5, 1.0)0.4 (0.3, 1.0)Nestl (8)Mean (SD)1.2 1.20.5 0.60.4 0.70.2 0.2Median (IQR )0.8 (0.5, 1.3)0.5 (0.1, 0.5)0.3 (0.0, 0.5)0.1 (0.0, 0.4)PepsiCo (4)Mean (SD)1.5 0.71.3 0.31.5 0.71.1 0.3Median (IQR )1.3 (1.0, 2.0)1.3 (1.0, 2.0)1.3 (1.0, 2.0)1.0 (1.0, 1.3)Pinnacle Food Group (6)Mean (SD)2.6 1.62.6 1.62.2 1.72.2 1.7Median (IQR )2.0 (1.5, 4.0)1.8 (1.5, 4.0)1.5 (1.5, 3.5)1.5 (1.5, 3.5)Safeway (11)Mean (SD)1.9 1.21.0 1.20.8 1.10.7 1.2Median (IQR )1.5 (1.0, 2.5)0.5 (0.0, 1.5)0.3 (0.0, 1.5)0.0 (0.0, 1.5)Sara Lee Corp. (9)Mean (SD)2.0 0.91.6 1.31.5 1.31.4 1.3Median (IQR )1.5 (2.0, 3.0)1.5 (0.3, 3.0)2.0 (0.3, 3.0)1.5 (0.3, 2.5)Schwan Food Company (7)Mean (SD)2.9 1.22.0 1.50.3 0.40.3 0.4Median (IQR )3.5 (2.5, 3.5)2.5 (0.0, 3.5)0.3 (0.0, 0.5)0.3 (0.0, 0.5)Tasty Baking Company (10)Mean (SD)2.8 2.20.5 0.70.2 0.10.2 0.1Median (IQR )2.0 (1.0, 4.0)0.3 (0.3, 0.3)0.3 (0.3, 0.3)0.3 (0.3, 0.3)Unilever (7)Mean (SD)1.5 1.01.1 1.00.8 0.90.7 0.8Median (IQR )2.0 (0.5, 2.5)0.5 (0.3, 2.0)0.3 (0.3, 2.0)0.3 (0.3, 1.5)Walmart Stores (5)Mean (SD)2.0 0.41.2 1.20.7 1.30.7 1.3Median (IQR )2.0 (2.0, 2.0)1.5 (0.0, 2.0)0.0 (0.0, 0.3)0.0 (0.0, 0.3)* Data were not collected in 2009. All products listing 0g TFA but still containing partially hydrogenated oils in the ingredients list were considered to still contain 0.25g/serving of TFA. IQR=interquartile range (25th, 75th percentile). Supplementary Table 4.Numbers of products originally containing e"0.5 g/serving TFA in 2007 that were discontinued by 2011, by food category. Food CategoryNo. of Products Discontinued by 2011 / Total Products in 2007(percent)*Breads4 / 19 (21.1%)Breakfasts1 / 9 (11.1%)Cakes and other pastries22 / 61 (36.1%)Cookies, biscuits and bars13 / 52 (25.0%)Crackers2 / 17 (11.8%)Doughnuts1 / 8 (12.5%)French fries/other potatoes4 / 22 (18.2%)Ice creams9 / 16 (56.3%)Margarines1 / 12 (8.3%)Meats and seafood14 / 55 (25.5)Muffins0 / 5 (0.0%)Pasta8 / 18 (44.4%)Pies5 / 27 (18.5%)Pizzas3 / 15 (20.0%)Popcorns1 / 12 (8.3%)Rolls2 / 12 (16.7%)*Chi-square test P <0.001 comparing the different proportions of discontinued products by food category. Supplementary Table 5.Sensitivity analyses evaluating TFA reformulations between 2007 and 2011 among all 360 major US brand-name food products containinge"0.5 g/serving TFA in 2007, including 90 products discontinued by 2011.* Year2007200820102011Number of products containing any TFA (% of total) 360 (100)251 (70 )208 (58)197 (55)Mean SD TFA content, g/serving1.9 1.5a1.1 1.3b0.8 1.2c0.7 1.1dMedian (25th,75th percentile) TFAcontent in g/serving1.5 (1.0,2.5)a0.5 (0.0, 1.5)b0.3 (0.0, 1.0)c0.3 (0.0, 1.0)d*Ninety productssold in 2007 and discontinued by 2011 were included in the analysis, based on theactual TFA contents of the products in the years they were sold and then assuming reformulation to contain 0g of TFA per serving in all years after discontinuation. Data were not collected in 2009. All products listing 0g TFA but still containing partially hydrogenated oils in the ingredients list were considered to still contain 0.25g/serving of TFA. 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